METOX 100 Unit
Botulinum Toxin Type A
Composition: Clostridium botulinum toxin type A
Ingredients: 100 units (U) Clostridium botulinum toxin type A
0.5mg Human serum albumin (EP)
0.9mg Sodium Chloride (USP)
Appearance: White/light yellow lyophilizate in a colorless transparent vial that becomes clear and transparent when dissolved in physiological saline
Dosage Form: Freeze-dried white powder for reconstitution with sterile, 0.9% sodium chloride solution (preservative free)
Storage method: Store at 2 ~ 8ºC in a refrigerator, in a hermetic container
Injection Site: Corrugator muscle/procerus muscle(forehead wrinkles), orbicularis oculi muscles(eye wrinkles), pre-tarsal orbicularis oculi(to treat blepharospasm), masseter muscle(jaw), platysma muscle(neck), dermis(skin).
Application Areas: Treatment of blepharospasm. Improvement of glabellar lines, eye wrinkles, neck wrinkles and other facial wrinkles. Relaxation of jaw muscles to provide a slimmer jawline. Reduction of pore size to provide a smoother skin appearance.
Maintenance: Period: 12 months
METOX 100 Unit
What is METOX 100 Unit?
Metox is a botulin toxin used for smoothing all kinds of wrinkles caused by daily facial movements. Metox stops nerval impulses to calm them, reducing wrinkles.
Characteristics of METOX 100 Unit
Metox has greats effects on the improvement of facial asymmetry caused by muscle activity, lip contouring, eyebrows and forehead mimic wrinkles, crow's feet, nasolabial folds, wrinkles in the neck, hyperhidrosis
How to Use METOX 100Unit
What is METOX 100 Unit?
Metox is a botulin toxin used for smoothing all kinds of wrinkles caused by daily facial movements. Metox stops nerval impulses to calm them, reducing wrinkles.
Characteristics of METOX 100 Unit
Metox has greats effects on the improvement of facial asymmetry caused by muscle activity, lip contouring, eyebrows and forehead mimic wrinkles, crow's feet, nasolabial folds, wrinkles in the neck, hyperhidrosis
How to Use METOX 100Unit
Preparation process before injection procedure using WonderTox 100 Unit
1. Take out Metox 100 Unit from the refrigerator
2. Before using Metox 100 Unit, check if there are any irregularities in the product’s appearance. This product is a white freeze-dried powder in a colorless and transparent vial.
3. After filling an appropriate-sized needle with an appropriate amount of sterile, preservative-free 0.9% sodium chloride solution, slowly introduce the solution into the vial. Dilute to 100 U/2.5ml (4 U/0.1ml). Check the concentration using the following tab
1. Take out Metox 100 Unit from the refrigerator
2. Before using Metox 100 Unit, check if there are any irregularities in the product’s appearance. This product is a white freeze-dried powder in a colorless and transparent vial.
3. After filling an appropriate-sized needle with an appropriate amount of sterile, preservative-free 0.9% sodium chloride solution, slowly introduce the solution into the vial. Dilute to 100 U/2.5ml (4 U/0.1ml). Check the concentration using the following tab
4. Metox 100 U should only be mixed with sodium chloride solution. Do not mix with other types of solutions or products. If the product bubbles up or is strongly agitated, the product’s properties change or become denatured. Therefore, make sure to slowly introduce the sodium chloride solution.
5. After Metox 100 U is dissolved in the sodium chloride solution, it should be injected into the patient within 24 hours. If the mixture is not injected into the patient immediately, store in the refrigerator at 2 ~ 8ºC. Even if the mixture is stored in the refrigerator, it should still be injected in the patient within 24 hours. Also, write on the label the date and time of when the product was dissolved. After dissolving, the product should be transparent, and should not contain any abnormal substances. If the product changes color or if foreign materials are detected, do not use this product and discard immediately.
6. Metox 100 U does not contain any preservatives. It is not recommended to use 1 vial for more than 1 patient. After usage, the remaining product should be discarded.
7. Since each botulinum toxin product may be manufactured with a different toxin unit, the toxin unit of one product cannot be converted to the unit of another product.
How to administer Metox 100 U
To address glabellar lines (forehead wrinkles): Using a 30 gauge needle, inject the dissolved product in the corrugator muscles and the procerus muscle (a total of 5 areas). 0.1ml of the product should be injected in each area, with a total of 20 U being injected.
When injecting into the inner corrugator supercilii muscle and the medial eyebrows, inject at least 1 cm from the edge of the eye. During injection, the needle should be aimed at the upper center, and the injection volume should be accurate. Careful attention should be paid to NOT inject Botulax 100 U into the blood vessel. To prevent Botulax 100 U from being injected into the blood vessel(exudation) below the orbital ridge, place the thumb or index finger below the orbital ridge prior to injection.
The corrugator muscle and the orbicularis oculi muscle move in the middle of the forehead to make glabellar folds on the face. The procerus muscle and the depressor supercilii muscle pull the forehead downward. These muscles create frown lines or wrinkles. Because the muscle position, muscle size, and use of muscle vary from person to person, the effective dose is determined by complete observation of the patient's ability to control the implanted surface muscles.
To address wrinkles around the eyes: Using a 30~33 gauge needle, administer 0.1ml(4U) each on 3 areas on one of the outer regions of the orbicularis oculi muscles (6 areas on both sides, total of 24 U).
5. After Metox 100 U is dissolved in the sodium chloride solution, it should be injected into the patient within 24 hours. If the mixture is not injected into the patient immediately, store in the refrigerator at 2 ~ 8ºC. Even if the mixture is stored in the refrigerator, it should still be injected in the patient within 24 hours. Also, write on the label the date and time of when the product was dissolved. After dissolving, the product should be transparent, and should not contain any abnormal substances. If the product changes color or if foreign materials are detected, do not use this product and discard immediately.
6. Metox 100 U does not contain any preservatives. It is not recommended to use 1 vial for more than 1 patient. After usage, the remaining product should be discarded.
7. Since each botulinum toxin product may be manufactured with a different toxin unit, the toxin unit of one product cannot be converted to the unit of another product.
How to administer Metox 100 U
To address glabellar lines (forehead wrinkles): Using a 30 gauge needle, inject the dissolved product in the corrugator muscles and the procerus muscle (a total of 5 areas). 0.1ml of the product should be injected in each area, with a total of 20 U being injected.
When injecting into the inner corrugator supercilii muscle and the medial eyebrows, inject at least 1 cm from the edge of the eye. During injection, the needle should be aimed at the upper center, and the injection volume should be accurate. Careful attention should be paid to NOT inject Botulax 100 U into the blood vessel. To prevent Botulax 100 U from being injected into the blood vessel(exudation) below the orbital ridge, place the thumb or index finger below the orbital ridge prior to injection.
The corrugator muscle and the orbicularis oculi muscle move in the middle of the forehead to make glabellar folds on the face. The procerus muscle and the depressor supercilii muscle pull the forehead downward. These muscles create frown lines or wrinkles. Because the muscle position, muscle size, and use of muscle vary from person to person, the effective dose is determined by complete observation of the patient's ability to control the implanted surface muscles.
To address wrinkles around the eyes: Using a 30~33 gauge needle, administer 0.1ml(4U) each on 3 areas on one of the outer regions of the orbicularis oculi muscles (6 areas on both sides, total of 24 U).
To treat blepharospasm: Blepharospasm is defined as the uncontrollable muscle movements of the eyelid. Botulax 100 Unit should be administered using a sterile, 27-30 gauge needle, and injected into the medial and lateral pre-tarsal orbicularis oculi of the upper lid and into the lateral pre-tarsal orbicularis oculi of the lower lid. The initial recommended dose is 1.25-2.5U, at 0.05 mL to 0.1 mL volume at each site. The initial effect of Metox 100 Unit is generally seen 3 days after being injected. Full effects are seen 1 to 2 weeks after injection. The effects last approximately 3 months. If the initial treatment is deemed insufficient (i.e. effects do not last longer than 2 months), then the dose can be increased up to two-fold in repeat treatment sessions. However, there seems to be little benefit from injecting more than 5.0 U per injection site. Patients may develop a tolerance if treatments for blepharospasm are administered more frequently than every three months. The cumulative dose of Botulax 100 Unit should not exceed 200 U in a 30-day period.
To address the masseter(jaw) muscle: Before getting the injections, it is important to have a consultation with a medical professional that will examine the jaw and face area to determine the injection site. A medical professional will clean the skin before the injection to reduce the risk of infection. A topical anesthesia to numb the area may be used. Next, the doctor will insert the thin needle into the masseter muscle. After the procedure is completed and the toxin is injected, the needle will be slowly withdrawn. The procedure may be repeated on the other side of the face.
It is important to AVOID rubbing and placing pressure on the treated area for 24 hours.
To treat neck wrinkles: During the injection into the neck area, it is important to contract and relax the platysma muscle multiple times, in order to let the doctor evaluate and select the right area that needs the injections. With the contraction of the muscle, the lines are more visible, and the doctor can grab the muscle and inject botulinum toxin into it. As botulinum toxin weakens the muscles, the motion of the platysma muscle becomes very limited, thanks to that the neck looks smoother by softening the wrinkles and lines. Moreover, as there are no involuntary contractions, the neck appears tighter as well, indirectly improving the appearance of jowls and jawline too.
To administer as skin botox: Skin botox is created by mixing 4 to 5 times more saline solution than the traditional dilution ratio for botulinum toxin procedures. This dilutes the toxin more thinly. The diluted solution should be administered into the dermal layer (skin), which is different from the traditional technique, which administers the toxin solution into the muscle. Skin botox should be injected in small amounts in several small increments in facial areas. Effects of skin botox include the tightening of pores, the reduction of fine lines, the reduced production of oil and sweat, and overall smoother appearance of skin.
To address the masseter(jaw) muscle: Before getting the injections, it is important to have a consultation with a medical professional that will examine the jaw and face area to determine the injection site. A medical professional will clean the skin before the injection to reduce the risk of infection. A topical anesthesia to numb the area may be used. Next, the doctor will insert the thin needle into the masseter muscle. After the procedure is completed and the toxin is injected, the needle will be slowly withdrawn. The procedure may be repeated on the other side of the face.
It is important to AVOID rubbing and placing pressure on the treated area for 24 hours.
To treat neck wrinkles: During the injection into the neck area, it is important to contract and relax the platysma muscle multiple times, in order to let the doctor evaluate and select the right area that needs the injections. With the contraction of the muscle, the lines are more visible, and the doctor can grab the muscle and inject botulinum toxin into it. As botulinum toxin weakens the muscles, the motion of the platysma muscle becomes very limited, thanks to that the neck looks smoother by softening the wrinkles and lines. Moreover, as there are no involuntary contractions, the neck appears tighter as well, indirectly improving the appearance of jowls and jawline too.
To administer as skin botox: Skin botox is created by mixing 4 to 5 times more saline solution than the traditional dilution ratio for botulinum toxin procedures. This dilutes the toxin more thinly. The diluted solution should be administered into the dermal layer (skin), which is different from the traditional technique, which administers the toxin solution into the muscle. Skin botox should be injected in small amounts in several small increments in facial areas. Effects of skin botox include the tightening of pores, the reduction of fine lines, the reduced production of oil and sweat, and overall smoother appearance of skin.
Precautions when using Metox 100 U
Metox 100 U should be discarded as medical waste once it has passed the expiration date. If the toxin needs to be deactivated (e.g. when spilled out), use diluted hypochlorite(0.5% or 1%) before discarding it as medical waste. Also, products that have come in direct contact with Metox 100 U should also be discarded as medical waste.
Metox 100 U is not recommended to be injected frequently. Frequency should not exceed one treatment every 3 months.
The recommended dosage, frequency of treatment, and administration methods of Metox 100 U should be strictly followed. Certified professionals administering Metox 100 U should fully understand the relevant neuromuscular and/or orbital anatomy of the treatment area, and also any alterations to the anatomy that have occurred due to prior surgical procedures. DO NOT use Botulax 100 Unit without a doctor’s prescription.
Metox 100 Unit and its effects may unintentionally spread and affect other areas and cause adverse symptoms. Symptoms may include asthenia, generalized muscle weakness, dysphonia, dysarthria, stuttering, urinary incontinence, breathing difficulties, dysphagia (swallowing difficulties), diplopia, blurred vision, and ptosis.
The following people SHOULD NOT receive Metox 100 Unit:
- Patients who have an allergic or hypersensitive reaction to the ingredients in this product
- Patients with neuromuscular junction disorders (dysfunction at location where nerves connect with muscles), including Myasthenia gravis, Lambert-Eaton syndrome, Amyotrophic lateral sclerosis. Using this product causes relaxation of the muscle, which can exacerbate the existing disorder.
- Patients who are pregnant, planning to get pregnant, or are currently nursing mothers
- Patients below the age of 16
Why is Metox 100 Unit recommended?
Metox 100 U should be discarded as medical waste once it has passed the expiration date. If the toxin needs to be deactivated (e.g. when spilled out), use diluted hypochlorite(0.5% or 1%) before discarding it as medical waste. Also, products that have come in direct contact with Metox 100 U should also be discarded as medical waste.
Metox 100 U is not recommended to be injected frequently. Frequency should not exceed one treatment every 3 months.
The recommended dosage, frequency of treatment, and administration methods of Metox 100 U should be strictly followed. Certified professionals administering Metox 100 U should fully understand the relevant neuromuscular and/or orbital anatomy of the treatment area, and also any alterations to the anatomy that have occurred due to prior surgical procedures. DO NOT use Botulax 100 Unit without a doctor’s prescription.
Metox 100 Unit and its effects may unintentionally spread and affect other areas and cause adverse symptoms. Symptoms may include asthenia, generalized muscle weakness, dysphonia, dysarthria, stuttering, urinary incontinence, breathing difficulties, dysphagia (swallowing difficulties), diplopia, blurred vision, and ptosis.
The following people SHOULD NOT receive Metox 100 Unit:
- Patients who have an allergic or hypersensitive reaction to the ingredients in this product
- Patients with neuromuscular junction disorders (dysfunction at location where nerves connect with muscles), including Myasthenia gravis, Lambert-Eaton syndrome, Amyotrophic lateral sclerosis. Using this product causes relaxation of the muscle, which can exacerbate the existing disorder.
- Patients who are pregnant, planning to get pregnant, or are currently nursing mothers
- Patients below the age of 16
Why is Metox 100 Unit recommended?
Metox is a great product for all customers that want to have safe and greats result in a short period of time. Cosmetic effect with METOX 100 U injections is observed after 3-7 days The duration of the effect is approximately 6-9 months, Additionally, Metox does not affect negatively any adjacent muscles or facial expression. Moreover, Metox provide excellent patient tolerance, assuring greats results with a painless treatment.
※ Caution
We, Medi-Fella Korea, do NOT take any responsibility for medical issues and problems that occur during cosmetic procedures.
We, Medi-Fella Korea, do NOT take any responsibility for medical issues and problems that occur during cosmetic procedures.